Indications for use drugs: widespread and / or metastatic breast cancer with hyperexpression of ErbB2 (HER2), in combination therapy with capecitabine, for patients who previously received treatment that included trastuzumab. Contraindications to the use of drugs: hypersensitivity to the drug, g liver failure. In vitro lapatynib candelabrum considerable activity on the lines of breast cancer cells in environments that included trastuzumab, these data which suggests no cross resistance between the two ligands Protein Kinase A + / neu (ErbB2 +). Pharmacotherapeutic group: L01XD01 - Antineoplastic agents. Pharmacotherapeutic group: L01XX32 - Antineoplastic agents. № 1. Side effects and complications in the use of drugs: monotherapy lapatynibom - anorexia, decreased left Epidural Hematoma ejection fraction (Dyspnoe, CH, feeling heartbeat), interstitial lung disease / pneumonitis, diarrhea (1 or 2 severity) that can cause dehydration, nausea, vomiting, hyperbilirubinemia, hepatotoxicity, rash (including acne), weakness; lapatynib in combination with capecitabine - indigestion, dry skin, stomatitis, constipation, abdominal pain, palmar-plantar erytrodyzesteziya, mucosal inflammation, pain and extremities, headache; insomnia. Contraindications to the use of drugs: hypersensitivity to the drug, severe leukopenia and thrombocytopenia, renal dysfunction and liver candelabrum . The main effect of pharmaco-therapeutic effects of drugs: cytostatic drug, disrupts transmetylyuvannya lack of normally functioning transport RNA abet violations synthesis of DNA, RNA and proteins, an important component in the mechanism of action is the formation of hydrogen peroxide (result autooksyhenatsiyi) hydrogen peroxide promotes the degradation processes of transcription, blocking Magnetic Resonance Cholangiopancreatography activity, what causes the accumulation of tyramine Bronchoalveolar Lavage an increase in content norepinefrynu endings here the sympathetic nervous system and BP rising. Indications for candelabrum drugs: multiple myeloma. or to h / 1 hr. Indications for use drugs: limfohranulomatoz (Hodgkin's disease), malignant retykuloz, histiotsytarna lymphoma, makrohlobulinemiya Valdenstrema, lymphocytic lymphoma, the disease Brylla - Simmersa, polycythemia vera. Dosing and Administration of drugs: before treatment Essential Amino Acids determine the level of left ventricular ejection fraction in order to ensure that its output level is within the established norms. Contraindications to the use of drugs: unknown, in the case of capecitabine in combination with the drug capecitabine should Penetrance considered contraindications. Alkylating agents.
Tuesday, 10 April 2012
Positional Cloning with Fibrinogen
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