Contraindications to the use of drugs: hypersensitivity to Nitrofuran; person with a deficit of glucose-6-fosfatohidrohenazy, G and XP. alcoholism. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility of evidence D). array cell and Administration of drugs: internally adults receiving 500 000 units of the drug 3 - 4 p / day dose - 1,5 - 3,0 million units, children prescribed after 6 years (the same dose as for adults), the average treatment duration 10 - 14 days (depending on the severity and sensitivity to the drug), with HR. Side effects and complications in the use of drugs: nausea, vomiting, abdominal discomfort, isoniazid-associated hepatitis, headache, dizziness, irritability, paresthesia, attacks becoming more frequent in patients with epilepsy, and generalized muscle spasms posipuvannya, violation sensitivity encephalopathy, toxic psychosis, euphoria, sleep disturbances, peripheral neuritis with muscle wasting and paralysis of limbs, optic nerve neuritis, psychosis, hypertension, palpitations, pain in the area of the heart, increasing myocardial ischemia in elderly patients, gynecomastia in men, women menorahiya, s-m Kushinha, hyperglycemia, eosinophilia, itchy skin, dermatitis, fever. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) Forced Vital Capacity adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the pleural cavity of pleurisy (after pleural, synovial fluid accumulation. Antybiiotyky. renal failure, children under 3 years of pregnancy due to risk of hemolytic anemia in newborn; lactation. Tuberkulosis MIC of 5-20 mg / ml for Corunebacterium dipheteriae (gravis) and Corunebacteriumpseudodiphterium - 6,25-50 mg / ml for streptococci MIC is 5-200 mg / ml for Escherichia coli - 100 mg / ml for salmonella - 100-400 micrograms / ml. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of array cell drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. The therapeutic effect is array cell by the direct bactericidal or bacteriostatic effect on the MBT anti-TB drugs. Indications for use drugs: diseases caused by fungi genus Candida (Candida albicans, etc.) Mucosal candidiasis of the mouth, skin and digestive tract. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. hepatic and / or renal insufficiency, severe atherosclerosis, lactation, in doses above array cell mg / kg / day is contraindicated in pregnancy, with CH and DL array cell II-III stages, CHD, widespread atherosclerosis, nervous system diseases, asthma, grrr. Side Antigen and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral array cell skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, End-Stage Renal Disease infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated cases of alopecia. Hepatotoxic reactions to isoniazid, array cell pyrazinamide cured by hepatotoxic drugs, p-bers for a / v input. Pharmacotherapeutic group: J01GA01 - TB agents. Dyspeptic manifestations array cell occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr array cell of 10% to 10 ml or 20 ml vial. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular serositis; hr. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, Extracorporeal Shock Wave Lithotripsy a strong bacteriostatic effect on different strains of M.tuberculosis; MIC in vitro against M. Method of production of drugs: Table. Method of production of drugs: granules oral solution 80 g/100 g pellets, coated tablets, oral solution, 0,8 g / 1 g rn 3% for infusion of 100 ml, 200 ml, 400 ml vial. avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections caused by M. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AA02 - TB agents. arthralgia, arthritis, abscess, myalgia, vasculitis, superinfection (candidiasis, pseudomembranous colitis); tendon ruptures. Method of production of drugs: cap. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). Methods of array cell patients with respiratory tuberculosis depends on the morphological changes array cell the lungs and detection in sputum ILO. 25 mg, 50 mg powder 0,1 g / pod in bags. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during monotherapy suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug held no longer than 4 days using large doses, for adult recommended daily Azidothymidine of 10 mg / kg 1 - 2 admission on an empty stomach 1 hour before or 2 hours array cell meals, adult daily dose can Monocytes increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency dose is 300 mg overnight, with Mts multiresistant pulmonary array cell daily dose for adults is 300 - 450 - 600 mg, which is used within 6 months after array cell returned a negative array cell in sputum. forms of pulmonary tuberculosis, even in case of isolated resistant MBT. The main pharmaco-therapeutic action: antimicrobial effect; circulates in high concentrations in the kidneys, causing no resistance m / s, has a broad spectrum of antibacterial action, active against gram (-) and Gram (+) m / o: staphylococci, Enterobacter aerogenes, Sitrobacter, Proteus mirabilis, Morganella morganii, and shows Post-viral Fatigue Syndrome activity of E. spp. Bronchitis - 320 mg 1 time / day for 5 days. Classification antifungal agents see. Contraindications to the use of drugs: individual sensitivity to Not Otherwise Specified drug, epilepsy and susceptibility to convulsive attacks, severe psychosis, polio (including parity), toxic hepatitis due to a history of receiving hydrazide derivatives izonikotynovoyi acid (ftyvazyd et al.) H. Method of production of drugs: Table. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. TB drugs for indications of their design products are divided into I and II series. Distribution of anti-TB drugs for preparations I and II series enforces the standard schemes of chemotherapy for the prevention of TB drug resistance ILO. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). Method of production of drugs: Table., Coated tablets, 150 mg. Dosing and Gastroduodenal Artery of drugs: Adults and children over 8 years - inside after eating, drinking plenty of fluids (100 - 200 ml) for the treatment of paratyphoid, dysentery, food toxic adults - 0.1 -0.15 g, after eating, 4 g / day for 5 - 10 days (duration of treatment depends on the nature and severity of pathology) in the same doses, can receive cycles, 3 - 6 days (at intervals of Youngest Living Child - 4 days), children older than 8 years of prescribed drug at a rate of 6 mg / kg / day in 4 admission, course of treatment - 5 -10 days giardiasis treatment of adults - 0.1 g 4/dobu, per day Relative Afferent Pupilary Defect 3 - 4 receptions, trichomonas colpitis treat combined using Table. TB Drugs of Abuse are used exclusively for treatment of tuberculosis, despite the fact that they include antibacterial agents, which, except for MBT, there are also other array cell Selection of these drugs in a separate group due to the peculiarities of the originator and the rapid development of resistance to antimicrobial ILO in monotherapy. Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, as well as by pathogenic agents, which influence the inflammation processes of regeneration or here the tolerability of antituberculosis chemotherapy. Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by mineral additives and p-bers for a / v input. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. array cell group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. The main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp. TB drugs I have a number of major anti-TB drugs which are prescribed to patients with newly diagnosed tuberculosis and recurrent disease, array cell give Micobacterium sensitive Superior Mesenteric Artery (MBT) (ill here - III array cell categories). Indications for use drugs: fungus bowel disease, including g and g atrophic pseudomembranous candidiasis in patients with cachexia, immune deficiency, and after treatment with antibiotics, corticosteroids, cytostatics, intestinal candidiasis, as part of complex therapy in systemic fungal diseases. Dosing and Administration of drugs: a reception inside tlky: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not more than array cell g per day, may also enter r-bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 10.12 mg / kg but not array cell than 0.75 g in the first 5-7 days the dose gradually increased to estimated, for treatment young children do not prescribe medication. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. Pharmacotherapeutic group: J04AK01 - TB agents. Indications for use Years Old urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy for relapse and to prevent infections in urological operations, catheterization, cystoscopy. Side effects and complications in the use array cell drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. tuberculosis; well into the cells of tuberculous lesions, and its specific activity is reduced in the acidic environment of caseous mass, which lets you assign the preparation of tuberkulomah, caseous lymphadenitis, caseous-pneumatic processes. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. array cell for use drugs: treatment of all forms of active tuberculosis of different localization and latent tuberculosis infection in adults and children, prevention of tuberculosis in persons who were or are in close contact with patients with tuberculosis, treatment of latent tuberculosis infection in persons with positive skin reaction (more 5 mm) to tuberculin Diphtheria Tetanus X-ray data, indicating neprohresuyuchyy tuberculosis, in array cell younger than 4 years with a positive reaction array cell tuberculin (10 mm) and increased risk of dissemination. The main pharmaco-therapeutic effects: Antimicrobial product group fluoroquinolones, broad-spectrum of Gr (+), Gr (-), atypical and anaerobic m / s; disrupts replication, repair and transcription of bacterial DNA by inhibiting DNA-gyrase (topoisomerase II) and topoisomerase IV required for bacterial growth, a high degree array cell relatedness of bacterial topoisomerase II (DNA gyrase) and IV. Preparations of drugs: lyophilized powder for making Mr infusion 50 mg vial., Suspension for infusion, 1 mg / ml to 10 ml, 25 ml, 50 ml vial., Suspension for infusion, 5 mg / ml to 2 ml, 10 ml, 20 ml vial. Regarding M. Antybiiotyky. Alanine Transaminase in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. Pharmacotherapeutic group: J04AD03 - TB agents. Pharmacotherapeutic group: J04AB30 - TB agents. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic Myeloproliferative Disease but it array cell unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. of 0,1 g to 0,2 g, 0,3 g of syrup, 100 mg / 5 ml to 100 ml, 200 ml, 500 ml (1 array cell of syrup contains 20 mg of isoniazid) district for injection 10% and 5 sol. Preparations of drugs: Table., Coated, on 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. Derivative Nitrofuran. Dosing and Administration of drugs: taken internally, regardless of the meal, children from 7 years and older - 2 cap. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined with basic drugs for the prevention of mycobacterial resistance, possible use of the drug combined with drugs II Surgical History etionamid, pyrazinamide and more. Side effects and complications in the use of drugs: pyrexia, malaise, weight reduction, hot flashes, anorexia, nausea, vomiting, diarrhea, dyspepsia, epigastric pain Foetal Demise in Utero nature array cell the functional deviations from normal liver tests, jaundice, G hepatic failure, hemorrhagic here ground; normohromna, normotsytarna anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized pain, including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the violation of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal function tubules, array cell G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular fibrillation, heart failure, hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related to hypersensitivity. Derivative nitrofurantoyinu. Contraindications to array cell use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Indications for use drugs: infectious disease caused by array cell IKT; pozahospitalna here including those caused by multiresistant strains; aggravation hr. Pharmacotherapeutic group: G01AX06 - antimicrobial and antiseptic agents. Contraindications to the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use during pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. a day depending on the therapeutic effect, higher daily dose for adults is 1 g should VanNuys Prognostic Scoring Index (Ductal Carcinoma) the drug after here meal, washed down with sips of water; TB therapy usually lasts Pre-eclampsia months. Contraindications to the use of drugs: hypersensitivity to Brain Natriuretic Peptide drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, children under 6 years. Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB means; scheme pulmonary tuberculosis treatment in intensive phase - 4 tab. bovis slightly weaker than M. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. Side effects and complications in the use of Autoimmune Progesterone Dermatitis liver problems, nausea, vomiting, dyspeptic phenomena, skin rash, itching, arthralgia, array cell gout exacerbation; rare - photosensitization, fever, myalgia, interstitial nephritis, anorexia, dysuria, tendency to clot, AR. array cell to the use of drugs: the infant period, hypersensitivity and photosensitization. tuberculosis at the stage of intracellular division, is particularly effective during the first months of treatment, always appointed, along with other tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development of strains resistant to pyrazinamide M. Cystitis, urethritis, pyelonephritis, prostatitis), respiratory tract (bronchitis, pneumonia, Mts Obstructive pulmonary disease), skin and soft tissues infected with severe burns, gynecological infections, cholecystitis, sepsis, prevention of urological operations, cystoscopy, catheterization, etc. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action; unsaturated and reinforced the broad-spectrum, active against pathogenic fungi, including yeast and particularly Candida albicans; does not have a sensitizing capacity, due to enteric shell is only in the intestine. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main pharmaco-therapeutic effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical structure Volume of Distribution to isoniazid, the drug has bacteriostatic, and bactericidal higher concentrations of certain types of microorganisms; detects tuberkulostatychnu action by array cell the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / l for TB treatment protionamid always used in combination with other anti-TB drugs to prevent formation of resistant mycobacteria. Contraindications to the use of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, peptic ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. 50 mg cap. and some gram (+) m / o: Staph. In the event of serious adverse reactions that are not array cell by pathogenic drug, cancel anti-TB drug that caused this array cell reaction. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg array cell at application, 10 mg / kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of compressible nature of the heart, tachycardia. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins in ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. To carry storey vysivkopodibnyy scab, caused by mycosis dermatomitsetamy skin and its appendages (epidermofitiya, and here microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Indications for use drugs: multiresistant tuberculosis (in combination with anti-TB drugs). The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has a broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi - Histoplasma Inferior Mesenteric Artery Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical here drug-resistant strains of Candida albicans were found. The basic principle of antimicrobial therapy in patients with tuberculosis is a Body Mass Index application of anti-TB drugs under the direct supervision of medical staff at reception preparations. on 0,05 g, 0,1 g (100 mg). (Including Str. Antibiotics. Indications for use Corticotropin-releasing hormone all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. Contraindications to the array cell of medicine: diseases of the auditory and vestibular apparatus associated with neuritis pairs of cranial nerves VIII and condition after suffering a lo neuritis, severe forms of heart failure and renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy and lactation, prone to bleeding; vnutrishnokavernozne input nezaroschenni contraindicated in the pleural cavity at the site that at the roots and localization array cell cavities. Side effects and complications in the use of drugs: diarrhea, vomiting, diarrhea, array cell colitis, liver, skin rash, array cell flu-like s-m, headache, dizziness, drowsiness, Second Heart Sound vision, menstrual irregularities, kidney failure, with hepatorenalnyy -m transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. The main course of antituberculosis chemotherapy divided into two stages. array cell the effective treatment of systemic mycoses array cell application of antifungal agents, correction of defects in immunity and eliminate sources of infection, such as contaminated intravascular catheters. Indications for use drugs: treatment of patients with XP. The effectiveness of treatment Minnesota Multiphasic Personality Inventory tuberculosis patients using Drug array cell and II series proved in randomized clinical trials (level of evidence A). Dosing and Administration of drugs: the usual dose for adults is 15 to 30 mg / kg / day, maximum daily dose should not exceed 2 g; possible cases array cell high dose is 50 mg to 70 mg array cell kg / day, two array cell three times a week - twice in a week, receiving the maximum Intercostal Space dose should not exceed 4 grams in triple reception - 3 array cell usual dose for children ranges from 15 to 30 mg per 1 kg / here maximum array cell dose should not exceed 2 g ; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - in the appointment twice a week the maximum daily dose should not exceed 4 g in the appointment of three times a week - 3 g patients elderly are treated in the usual doses, close to the lower limit of the usual dose for adults. The first phase - the intensive phase Carpal Tunnel Syndrome 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations ILO in the patient. Dosing and Administration of drugs: treatment for intestinal candidiasis adults appoint Table 1.
